First post on the Chow boards, so go easy on me.
The best barbecue is cooked with wood (versus the electricity used by a growing number of joints), and so will the places I recommend:
Parker's in Wilson, NC
I know you didn't ask, but my favorite western joint without a doubt is Lexington Barbecue #1 in Lexington, NC. It's worth a trip, if you ever find yourself in the area.
P.S.: Totally forgot about B's--good call whoever said it.