How do you feel about the Castro? My girlfriends and I love going to 2223 Market for brunch and we are in our 30's and, for the most ,part married with kids. They got great food, fun atmosphere and all reasonably priced. If you are going to the Academy of Science, Park Chow on 9th/Lincoln may be worth looking into- not too far from the park. Both restaurants are American style and very delicious.